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Beta blockers(pharmacokinetics)
T ½ ESRD Range of dosing % removal with HD
Metoprolol 5 hrs 50‐200 mg BID HIGH
Atenolol <120 hrs 25‐50 mg q48 75 %
Carvedilol 8.5 hrs 6.25‐25 mg BID NONE
Labetalol 7 hrs 100‐1200 mg BID NONE
Propranolol 4.5 hrs 40‐120 mg BID <5%
Atenolol is excreted mainly in kidney T1/2 is prolonged